Premium blood disorder health recommendations by Arthur Billings? What is ITP? Immune thrombocytopenia (formerly known as idiopathic thrombocytopenic purpura) is a medical term for an autoimmune disorder (immune) causing a shortage of platelets (thrombocytopenia) and bruising (purpura). What is the cause of ITP? ITP is an autoimmune disease in which the immune system mistakes the platelets as being foreign and destroys them. It can follow a virus, vaccination or certain medications, but for most people the cause is unknown.
Arthur Nathaniel Billings on blood disorder treatments : Many people with ITP have a platelet count in single figures, and on rare occasions there are not enough circulating platelets to be counted, thus the count is given as 0. The number of platelets circulating in our bodies fluctuates all the time, and thus no two consecutive platelet counts are likely to be exactly the same either in a healthy person or in an ITP sufferer. What is the difference between ITP and hæmophilia? Haemophilia is inherited and permanent, ITP is not inherited, and can go into remission. Hæmophilia patients are deficient in one of the 12 factors which act together to form a blood clot. ITP patients are short of platelets which work independently as the initial plug to stop blood leakage, but the rest of the clotting mechanism works normally. Platelet infusions are only used in emergencies as transfused platelets, like the patient’s own platelets, are destroyed by their immune system in a matter of hours.
What are platelets? Platelets are one of the three types of blood cell, along with red and white blood cells. Platelets are small and sticky and their job is to prevent bruising and stop bleeding after an injury. Platelets, like red and white blood cells, are formed in the bone marrow. A rough idea of how many platelets are circulating in the bloodstream (platelet count) can be made from a sample of blood. The normal platelet count is between 150 and 400 x 109/L. In many cases of ITP, the platelet count is less than 30 x 109/l at presentation. A low platelet count is called “thrombocytopenia”.
How is idiopathic thrombocytopenic purpura treated? Specific treatment for idiopathic thrombocytopenic purpura will be determined by your health care provider based on: Your age, overall health, and medical history; Extent of the disease; Your tolerance for specific medications, procedures, or therapies; Expectations for the course of the disease; Your opinion or preference. When treatment is necessary, the two most common forms of immediate treatment are steroids and intravenous gamma globulin. Read extra details on Arthur Nathaniel Billings.
Medications (including over-the-counter medications) can cause an allergy that cross-reacts with platelets. Infections, typically viral infections, including the viruses that cause chicken pox, hepatitis C, and AIDS, can prompt antibodies that cross-react with platelets. Pregnancy, Immune disorders, such as rheumatoid arthritis and lupus, Low-grade lymphomas and leukemias may produce abnormal antibodies against platelet proteins. Sometimes the cause of immune thrombocytopenic purpura is not known.